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College of Veterinary Medicine, NPUST
Dean

CURRICULUM VITAE

NAME

SHIH-CHU CHEN, Professor and Dean MSc DVM, Ph.D(Chinese Evrsion) 

DEPARTMENT

Department of Veterinary Medicine and Graduate Institute of Animal Vaccine Technology, National Pingtung University of Science and Technology Neipu, Pingtung, Taiwan, ROC.

E-MAIL

scchen@mail.npust.edu.tw

TEL

+886-8-7740569

FAX

886-8-7740571

EDUCATION

DVM 1979.....Department of Veterinary Medicine, National Pingtung Polytechnic Institute, Neipu, Pingtung, Taiwan, ROC

MS 1987......Department of Veterinary Medicine National Chung Hsin University, Taiwan, ROC

PhD 1996……Institute of Aquculture, University of Stirling, Stirling, Scotland, UK

RESEARCH TRAINING AND PROFESSIONAL EXPERIENCE

l Teaching Assistant.....Department of Veterinary Medicine , National Pingtung Institute of Agriculture, Taiwan , 1983-1988

l Lecturer..... Department of Veterinary Medicine, National Pingtung Polytechnic Institute, Taiwan., 1988-1992

l Associate professor...Department of Veterinary Medicine, National Pingtung Polytechnic Institute, Taiwan., 1992-2001

l Professor…..Department of Veterinary Medicine, National Pingtung University of Science and Technology, Taiwan, 2001

l Professor and Director….. Department of Veterinary Medicine and Graduate Institute of Animal Vaccine Technology, National Pingtung University of Science and Technology, Taiwan., 2005-2008

l Professor and Director…..Graduate Institute of Animal Vaccine Technology,National Pingtung University of Science and Technology, Taiwan., 2005-2011

l Professor…..Department of Veterinary Medicine, College of Veterinary Medicine National Pingtung University of Science and Technology, Taiwan., 2011

FIELD OF PRESENT SCIENTIFIC INTEREST

l Pathogenicity and immunogenicity of extracellular products from bacteria

l General pathology of Fish Diseases

l Fish vaccine development

SHIH-CHU CHEN (PUBLICATIONS)

Ø REFERRED PAPERS

l Chen, S.C., Tung, M. C., C.F. Lu and S.T. Huang. (1984) Sensitivity in vitro of various chemotherapeutic agents to Edwardsiella tarda of pond-cultured eels CAPD, fisheries Series No. Reports on Fish Diseases Research (VI) Republic of China, 100-106.

l Chen, S.C., S.S. Tsai, Y. H. Wu., S. C. Lin, and C.F. Chang (1984). Congestive cardiomyopathy in ducks. Federation of Asia Veterinary Association. November 172-177, Taipei, Taiwan, ROC.

l Tung. M. C., S. S. Tsai., L. F. Ho., S. T. Huang and S. C. Chen. (1985) An acute septicemic infection of pasteurellla organism in pond-cultured from snake-head fish (channa maculata Lecepede) in Taiwan. Fish Pathology, 20, 143-148. (SCI)

l Tung, M.C. S. S. Tsai., Chen, S.C. 1985.Study on Vibrio anguillarum infection in cultured milk fish (Chanos chanose) in Taiwan COA Fisheries Series No, 4 Fish Diseases Research (VII) 27-37.

l Tung, M.C., Chen,S.C.and Tsai, S. S. (1985) General septicemia of Streptococcus infection in caged cultured tilapia in Southern Taiwan. COA Fisheries series No. 4 Reports on Fish Diseases Research (VII) Republic of China. 95-105.

l Chang, G.N., and Chen, S.C. (1988) study on the toxicity and antigenicity of a heat -stable extracellular of Hemophilus pleuropneumonia (serotype I) The 8th Seminar on Science and Technology Respiratory and Reproductive system of Swine, Tokyo, Japan, 101-115.

l Chen, S.C.Tung, M. C., and Tsai W. C. (1989) An epizootic in Formosa snake-head fish (Chamma maculata Lecepede) caused by Nocardia asteroides in fresh water pond in Southern Taiwan. COA Fisheries Series No. 15 Reports on Fish Diseases Research (IX) Republic of China 95-105.

l Chen, S.C. and C.I. Liu (1989) Extracellular products of Vibrio anguillarum (I) Studies on Pathogenicity of  extracelluar products of Vibrio anguillarum in fish COA Fisheries No Reports on Fish Diseases Research (IX) Republic of China 49-60.

l Chen, S.C. and C. I. Liu (1989) Extracellular products of Vibrio anguillarum (II) Studies on immunogenicity  of  extracelluar products of Vibrio anguillarum in eel COA Fisheries No Reports on Fish Diseases Research (IX) Republic of China 61-69.

l Tung, M. C., Chen, S. C., Tsai, Y. R., Tsai, Y. R., and S. S. Juaug. (1989) A severe infestation of Centrocestus formosanus in the pond cultures loach, Misgurnus anguillicaudatus, in Southern Taiwan, Symposium on Technology and Vocational Education Taiwan, ROC. 6427-6434.

l Chen, S.C. and M.C. Tung. (1990) Infection of cercaria and metacercaria of Centrocestus formosanus in loach, mouse and duckling. Journal of Chinese Society of veterinary Sceince 16:153-161.

l Chu, C. S. Tung, M.C. Ku, T. J., Chen, S.C. and F. S. Lin. (1990) Glugea plecoglossi infection in pond-cultured ayu, Plecoglossus altivelis, in North Taiwan COA Fisheries Series No. 24 Reports on Fish Diseases research (X) Republic of China 60-69.

l Chen, S.C. and M. C. Tung. (1990) An epizootic in large mouth bass (Micropeterus salmoides Lacepede) caused by Nocardia asteroides in fresh pond in Southern Taiwan. Journal of Chinese Society of veterinary Sceince 17:15-22.

l Tung, M. C., Chen, S.C. Chern, R. S. and C. P. Cheng. (1990) Candida infection in pond cultured Macrobrachium rosenbergii in Taiwan Japan-ROC Symposium on Fish Diseases.

l Tung, M. C., Juang, S. S., Cheng, A. K., Lee, C. S., Tsai, C. S., Chen, S.C., and Chern, R. S. (1991) Study on shrimp diseases under the different environmental systems of the cultured grow out ponds in Pingtung area. Symposium on studies on environment and improvement in culture shrimp.

l Tung, M. C. and S.C.Chen (1991) First report on lymphocytic diseases virus infection on pondcultured black-spotted grouper (Epinephelus amblycephalus blaaaker) and gray Snapper (Lutjanus argentimaculatus Forsska) in Taiwan Journal of Chinese Society of veterinary Sceince 17(2):81-88.

l Chen, SC.1992 Study on the pathogenicity of Nocardia asteroides to formosa snakehead, Channna maculata, (Lacepede) and Large mouth bass, Micropeterus salmoides (Lecepede) Journal of Fish Diseases 15, 47-53. (SCI)

l Chen, S. C. 1992 Study on the pathogenicity of Nocardia asteroides to Large mouth bass, Micropeterus salmoides (lecepede) Fish Pathology 27(1) 1-5. (SCI)

l Chen S.C. (1992) In vitro susceptibiity of Nocardia to several commonly used disinfectant. Journal of Fish Disesaes, 16, 345-348. (SCI)

l Chen, S.C. and P. C. Wang. 1993 In Vitro activity of antimicrobial agent to Nocardia Journal of Fish Diseases 16, 269-272. (SCI)

l Chen, S.C. Wang, P. C. and Tung M. C. 1994 Studies on the pathogenicity of Nocardia asteroides to the grouper, Epinephelus suillus (Cuvier and Valenciemes) Journal of Chinese Veterinary Science 20: 103-108.

l Chen, S.C., Tung, M.C., Chen, S.P., Tsai, J.F., Wang, P.C., Chern, R.S., Lin, S.C. and Adams, A. (1994) Systemic granuloma caused by a rickettsia-like organism infection in nile tilapia , Oreochronuis nilotica (Linnaeus), From Southern Taiwan. Journal of Fish Diseases 17: 591-599. (SCI)

l Adams, A., Thompson, K. D., Morris, D., Farias, C., and S.C.Chen (1995) Development and use of monoclonal antibody probes for immunohistochemistry, ELISA and IFAT to detect bacterial and parasitc fish pathogens. Fish and Shellfish Immunology, 5:537-547. (SCI)

l Adams, A., Thompson, K.D. McEwan, H., Chen, S.C. and  Richards, R.H. (1996) Development of monoclonal antibodies to Mycobacterium spp. isolated from snakehead (Channa striatus) and Siamese fighting fish (Betta spledens ) Journal of Aquatic Animal Health 8:206-215. (SCI)

l Chen, S.C., Yoshida T., Adams, A., Thompson, K.D. and Richards, R.H. (1996) Immune response of rainbow trout, Oncorhynchus mykiss, to extracellular products of Mycobacterium spp. Journal of Aquatic Animal Health.8:216-222. (SCI)

l Yoshida, T., Yamada, Y., Sakai., M., Inglis, V.,  Xie, X. J., Chen, S.C., and Kruger, R. (1996) Associated of the cell capsule with anti-opsonophagocytosis in b-hemolytic Streptococcus spp. isolated from rainbow trout. Journal of Aquatic Animal Health, 8:223-228. (SCI)

l Chen, S.C., Adams, A. and Richards, R.H. (1997) Extracellular products from Mycobacterium spp. in fish. Journal of fish Diseases. 20:19-25. (SCI)

l Chen, S. C., Adams, A., Thompson, K. D., and  Richards, R. H. (1997) Development of monoclonal antibodies to the extracellular products of Mycobacteria sp. isolated from snakehead (Channa  striatus) and reference strain, Mycobacterium chelonae. Journal of Aquatic Animal Health.9:86-98 (SCI)

l Chen, S. C., Adams, A., Thompson, K. D., and  Richards, R. H. (1997)A comparison of the antigenicity of the extracellular products (ECPs) Whole cell sonicates (WCS) from Mycobacterium spp. in Rabbits, mice and fish by western blotting and enzyme-linked immunosorbent assay. Journal of Fish Diseases, 20:427-442 (SCI)

l Chen, S. C., Yoshida, T. Adams, A., Thompson, K, D. and Richards, R. H (1998) Non-specific immune response of niletilapia Orechromis nilotica, to the extraccellular products of Mycobacterium spp. and to various adjuvants. Journal of Fish Diseases, 21:39-46. (SCI)

l Chen, S. C., Adams, A., Thompson, K. D., and Richards, R. H.(1998) Electron microscope studies of the in vitro phagocytosis of Mycobacterium spp. by rainbow trout head kidney macrophages Diseases of Aquatic Organisms,32:99-110. (SCI)

l Thompson K.D, Lilley J. H., Chen S.C, Adams A., Richards RH (1999) The immune response of rainbow trout (Oncorhynchus mykiss) against Aphanomyces invandans Fish and Shellfish Immunulogy 9,195-210. (SCI)

l Chen Shih-Chu Jie-Lin Lee, CCLai, Yeou-Wei Gu Chen-Tain Wang, Hong-You Chang and K-H Tsai (2000) Nocardiosis in seabass, Lateolabrax japonicus in Taiwan. Journal of Fish Diseases 23, 299-308. (SCI)

l Chen, Shih-Chu Pei-Chi Wang , Ming-Chen Tung, Kim D Thompson, Alexandra Adams A (2000) Piscirickettsia salmonis-like organism in grouper, Epinephelus melanostigma in Taiwan. Journal of Fish Diseases 23, 415-418 (SCI)

l Corrina Tan, Bin Huang, Siow Foong Chang, Gim Hue Ngoh, Barry Munday, Shih-Chu Chen and Jimmy Kwang (2001) Determination of the complete nucleotide sequence of the RNA1 and RNA2 of the Greasy Grouper (Epinephelus Tauvina) nervous necrosis virus, Singapore strain. Journal of General Virology 82: 647-653 . (SCI)

l Chen, Shih-Chu Ren-Jeng Kou, Ching-Tz Wu, and Pei-Chi Wang (2001) Mass mortality by Sphaerospora-like myxosporidean infestation in juvenile cobia, Rachycentron canadum (Linnaeus) marine cage cultured in Taiwan. Journal of Fish Diseases 24, 189-196 (SCI).

l Chen, S-C ., K D Thompson, A Adams and R H. Richards (2001) The production of a lymphokine (macrophage activating factor) by rainbow trout (Oncorhynchus mykiss) leukocytes stimulated with the extracellular products of Mycobacterium spp.  Journal of Fish Diseases  24, 217-224 (SCI)

l Chen, Shih-Chu Yu-De Lin, Li-Lin Liaw, and Pei-Chi Wang (2001) Lactococcus garvieae infection in the giant freshwater prawn Macrobranchium rosenbergii confirmed by polymerase chain reaction and 16S rDNA sequencing Diseases of Aquatic Organisms  45,45-52 (SCI)

l S-C Chen, L-L Liaw, H-Y Su, S-C Ko, C-Y Wu, H-C Chaung, Y-H Tsai, K-L Yang, Y-C Chen, T-H Chen, G- R Lin, S-Y Cheng, Y-D Lin, J-L Lee, C-C Lai ,Y-J Weng, S-Y Chu  (2002) Lactococcus garvieae, a bacterial infection in grey mullet, Mugil cephalus. Journal of Fish Diseases 25, 727-732 (SCI)

l Yoshiki Gushiken, Tsuyoshi Ooyama Shih-Chu Chen and Masahiro Sakai* (2002) Sequencing of 16S-23S rRNA internal transcribed spacer and their Application in the identification of Nocardia seriolae by PCR. Aquaculture Research 33, 1195-1198 (SCI)

l Shih-Chu Chen, Tung-Hung Chen, Pei-Chi Wang, Yu-Chi Chen, Ju-Ping Huang, Yu-De Lin, Hso-Chi Chaung, Li-Ling Liaw (2003) Metschnikowia bicuspidata and Enterococcus faecium coinfection in giant freshwater prawn, Macrobranchium rosenbergii Diseases of Aquatic organisms, 55:161-167 (SCI)

l Hung-Yi Su, Winston TK Cheng, Shih-Chu Chen, Chen-Tse Lin, Yi-Yang Lien, Hung-Jen Liu, R. Stewart Gilmour (2004) Mouse keratinocytes express C98, a novel gene homologous to bcl-2, that is stimulated by insulin-like growth factor1 and prevents dexamethasome-induced apoptosis Biochimica et Biophysica Acta  (BBA) 1676 : 127– 137  (SCI)

l Hung-Yi Su, Hung-Jen Liu, Shih-Chu Chen, Chen-Tse Lin, Yi-Yang Lien, Winston TK Cheng,  (2004) A novel gene homologous to teashirt is differentially expressed in neonatal mouse skin during development of hair follicles. Molecular Biotechnology 28, 9-20 (SCI)

l Su HY, Wang PC, Lien YY, Tsai MA, Liu SS, Wu KC, Hsieh CH, Shih-Chu Chen, (2005) Upregulation of an actin-like gene expression in giant freshwater prawn, Macrobrachium rosenbergii in response to the infection of Metschnikowia bicuspidata” Diseases of Aquatic organisms 66:175-180 (SCI)

l Pei-Chi Wang, Ju-ping Huang, Ming-An Tsai, Shu-Yun Cheng, Shin-Shyong Tsai1 Shi-De Chen, Shih-Ping Chen, Shih-Hau Chiu, Li-Ling, Liaw, Li-Teh Chang, Shih-Chu Chen (2005) Systemic infection of Kudoa lutjanus n. sp.(Myxozoa: Myxosporea) in red snapper Lutjanus erythropterus from Taiwan Diseases of Aquatic organisms 67:115-124

l Jian-Lin Lee, Shu-Yung Chu, Zan-Sheng Yu  Chien-Yu Lee, Chin-Chu Lai, Chung-Shun Hung, Jiann-Hsiung Wang, Zong-Bing Wu, Shih-Chu Chen, Tsung-Chou Chang and *Shinn-Shyong Tsai  (2006) Identification and Survey on Gram-Positive Streptococcus-Like Organisms Isolated from Grey Mullet ( Mugil cephalus Linnaeus ) Taiwan Vetyerinary Journal, 32:136-145.

l Y.Y. Lien , S.C. Sheu, H.J. Liu, S.C. Chen, M.Y. Tsai , S.C. Luo, K.C. Wu, S.S. Liu , H.Y. Su  (2007) Cloning and nucleotide sequencing of the second internal transcribed spacer of ribosomal DNA for three species of Eimeria from chickens in Taiwan  The Veterinary Journal Jan;173(1):184-189. (Veterinary Sciences, Impact factors:1.156, 27/124)

l C-Y Hsieh, Z-B Wu, M-C Tung1, C Tu, S-P Lo, T-C Chang, C-D Chang, S-C Chen, Y-C Hsieh and S-S Tsai In situ hybridization and RT-PCR detection of Macrobrachium rosenbergii nodavirus in giant freshwater prawn, Macrobrachium rosenbergii (de Man), in Taiwan, Journal of Fish Diseases 2006, 29, 665–671

l Wang C-Y C., H-S Shie, S-C Chen, J -P Huang, I -C Hsieh, M-S Wen, F-C Lin,  D. Wu (2007)  Lactococcus garvieae infections in humans: possible association with aquaculture outbreaks . International Journal of Clinical Practice (SCI). 61:67-83

l Chen SC, Chen YC, Kwang J, Manopo I, Wang PC, Chaung HC, Liaw LL, Chiu SH. (2007) Metschnikowia bicuspidata dominates in Taiwanese cold-weather yeast infections of Macrobrachium rosenbergii. Dis Aquat Organ. 2007 May 9;75(3):191-9

l Pei-Chi Wang, Yu-De Lin, Li-Ling Liaw, Red-Shiung Chern* and Shih-Chu Chen  (2008) Lactococcus lactis subspecies lactis also causes white muscle disease in farmed giant freshwater prawns Macrobrachium rosenbergii Diseases of Aquatic organisms 79:9-17

l Yoshiko Shimahara, Atsushi Nakamura, Ryohei Nomoto, Toshiaki Itami, Shih-Chu Chen and Terutoyo Yoshida (2008) Genetic and Phenotypic Comparison of Nocardia seriolae in Japan. Journal of Fish Diseases 31:481-488

l Yoshiko Shimahara, Atsushi Nakamura, Shih-Chu Chen, Toshiaki Itami and Terutoyo Yoshida (2008) Enzymatic profiles of the bacterial fish pathogen, Nocardia seriolae analyzed by RapID yeast plus System. Bulletin of the faculty of Agriculture, University of Miyazaki 54:39-45.

l Wang Pei-Chyi, Shi-De Chen, Ming-An Tsai, Y-J Weng and S-Y Chu,Red-Shiung Chern* 2, and Shih-Chu Chen*, (2009) Nocardia seriolae infection in the three striped tigerfish Terapon jarbua, (Forsskål) Journal of Fish Diseases 32 (4): 301-310.

l Abdelsalam M., K. Nakanishi, K. Yonemura, T. Itami, SC. Chen and T. Yoshida (2009) Application of Congo red agar to detect Streptococcus dysgalactiae isolated from diseased fish Journal of Applied Ichthyology. 25(4) August 2009 , pp. 442-446  (Fisheries 0.638 ; 30/40)

l Abdelsalam M., S CChen and T. Yoshida 2009 Surface properties of Streptococcus dysgalactiae strains isolated from marine fish Bull. Eur. Ass. Fish Pathol., 29(1), 15-23 (Fisheries 0.430 ; 36/40)

l Yoshiko Shimahara, Yun-Fen Huang, Pei-Chyi Wang, Terutoyo Yoshida, and Shih-Chu Chen (2009) Genetic and Phenotypic Comparison of Nocardia seriolae in Taiwan. Aquaculture 294 (3) 165–171(2008 Fisheries 1.678 ; 9/40)

l Combined immersion and oral vaccination of Vietnamese catfish (Pangasianodon hypophthalmus) confers protection against mortality caused by Edwardsiella ictaluri 2009 N. H. Thinh , T. Y. Kuo , L. T. Hung , T. H. Loc , S. C. Chen , Ø. Evensen , H. J. Schuurman **Nguyen H Thinh, , Fish and Shellfish immunology 27 (6):773-776 (Veterinary science 2/135, 3.161)

l Abdelsalam M. Chen S.C. & T. Yoshida  (2010)  Phenotypic and genetic characterizations of Streptococcus dysgalactiae strains isolated from marine fish collected in Japan and other Asian countries FEMS Microbiology Letters :). January 302 (1),32–38. (Microbiology: 53/91, 2.021)

l Yoshiko Shimahara, Yun-Fen Huang, Ming-An Tsai, Pei-Chyi Wang, Terutoyo Yoshida, and Shih-Chu Chen*  (2010) Immune Response of Largemouth bass, Micropterus salmoides, to Whole Cell of Different Nocardia seriolae.  Fisheries science (2008 Fisheries 0.781 ; 26/40) 22 April, 76(3) :489-494(SCI)

l M. Abdelsalam, S. C. Chen, and T. Yoshida1* (2010) Dissemination of streptococcal pyrogenic exotoxin G (spegg) with an IS-like element in fish isolates of Streptococcus dysgalactiae FEMS Microbiology letter  309 (1),105–113. Aug 1;309(1):105-13

l Yoshiko SHIMAHARA, Yun-Fen HUANG, Yao-Lin LI, Ming-An TSAI, Pei-Chi WANG and Shih-Chu CHEN,* (2010)  Growth Characteristics and Morphological Changes of Fish Pathogen Nocardia seriolae in Submerged Culture. Aquaculture science 58 (3), 429-431.

l LiTing Cheng, Chung-Yi Chen, Ming-An Tsai, Pei-Chyi Wang, Jung-Pin Hsu, Red-Shyong Chern ,  Shih-Chu Chen* ( 2011)  Koi herpesvirus epizootic in cultured carp and koi in Taiwan. Journal of Fish diseases  Jul;34(7):547-554

l LiTing Cheng, Wen-Hui Lin, Pei-Chyi Wang, Ming-An Tsai, Jung-Pin Hsu, Red-Shyong Chern, Shih-Chu Chen*(2011) Epidemiology and phylogenetic analysis of Taura syndrome virus in cultured Pacific white shrimp Litopenaeus vannamei B. in Taiwan. Diseases of Aquatic Organism Nov 3;97(1):17-23.

l Ming-An Tsai, Ping-Yueh Ho, Pei-Chyi Wang, Li-Ling Liaw and shih-Chu Chen (2012) Development of Multiplex PCR for Detection of Five Common Gram-negative Bacteria in Aquatic Animals in Taiwan Journal of Fish Diseases. Jul; 35(7):489-95

l Ming-An Tsai, Pei-Chyi Wang, Li-Ling Liaw, Terutoyo Yoshida and Shih-Chu Chen (2012) Comparison of genetic characteristics and pathogenicity of Lactococcus garvieae isolated from aquatic animal in Taiwan Revised to Diseases of Aquatic Organisms. Dec Vol. 102: 43–51

l Issei Nishiki, Yasushi Horikiri, Shih-Chu Chen, Toshiaki Itami, Terutoyo Yoshida*(2012) Expression of the serum opacity factor gene and the variation in its upstream region in Streptococcus dysgalactiae isolates from fish. The Journal of General and Applied Microbiology  Dec; 58(6), 457-463  Impact Factor: 0.98  2.337 (60/112 (Microbiology);: 71/157 (Biotechnology & Applied Microbiology)

l M-A Tsai , P-C Wang, T Yoshida, L-L Liaw, S-C Chen* (2013) Development of a sensitive and specific LAMP PCR assay for detection of fish pathogen Lactococcus garvieae. Diseases of Aquatic Organisms  2013 Feb 28;102(3):225-35

l Wen-Hsin Chang, Sung-Yi Yang, Chih-Hung Wang, Ming-An Tsai, Pei-Chyi Wang, Tzong-Yueh Chen, Shih-Chu Chen* and Gwo-Bin Lee* (2013)  Rapid isolation and detection of aquaculture pathogens on an integrated microfluidic systems using loop-mediated isothermal amplification. Sensors and Actuators B, April 180 96–106 Chemistry, Analytical, Impact factor: 3.370; Ranking :13/73) SCI)

INSTRUMENTS & INSTRUMENTATION, Impact factor: 3.898 Ranking : 3/58=5.2% (Co-corresponding author) Web 4.4 welcome

LiTing Cheng, Wen-Hui Lin, Pei-Chyi Wang, Ming-An Tsai, Jung-Pin Hsu, Shih-Chu Chen*  (2013) White spot syndrome virus epizootic in cultured Pacific white shrimp Litopenaeus vannamei B. in Taiwan. Journal of Fish Diseases 2013, 36 (12), 977–985

Ming An Tsai , Pei-Chi Wang, Thanh-Trung Cao, Li-Ling Liaw, Shih-Chu Chen*(2013) Immunoprotection of glyceraldehydes-3-phosphate dehydrogenase from Lactococcus garvieae against Lactococcosis in tilapia.   The Journal of General and Applied Microbiology  Impact Factor: 0.98   59, 437-449

Chin-I Chang *, Chia-Fang Lee, Jyh-Ming Tsai, Chia-Che Wu, Li-Hao Chen, Shih-Chu Chen and King-Jung Lin (2013) Development of a selective and differential medium for capsulated Lactococcus garvieae. Journal of Fish Diseases  2013 0709 (Accepted) 2013 Aug 19. doi: 10.1111

Mohamed Abdelsalam, Alaa Eldin Eissa, SC Chen, (2013) Genetic diversity of geographically distinct Streptococcus dysgalactiae isolates from fish. (submitted) Journal of Advanced Research (accepted).

M. Abdelsalamaı, M. Fujinob, A.E. Eissaa,c, S.C. Chend,e, M. Warda fı, (2014) Expression and genetic localization of NAPlr in Piscine S. dysgalactiae isolates and their adherence pattern characterization (accepted)

Cao Thanh Trung, Ming-An Tsai, Chang-Dar Yang,  Pei-Chyi Wang, Tsun-Yung Kuo, Hsu-Chung Gabriel Chen,  Shih-Chu Chen (2014) Vaccine Efficacy of Glyceraldehydes-3-Phosphate Dehydrogenase (GAPDH) from Edwardsiella ictaluri against Edwardsiella tarda in tilapia  The Journal of General and Applied Microbiology(submitted and revised)

Ming-An Tsai, Pei-Chyi Wang Terutoyo Yoshida and Shih-Chu Chen (2014) Genetic characteristics of Streptococcus dysgalactiae isolated from Cage Cultured Cobia, Rachycentron Canadum Journal of Fish Diseases (in press)

Pei-Chi Wang, Ming-An Tsai, Yu-Chi Liang, Yanting Chan and Shih-Chu Chen (2014) Nocardia seriolae, a causative agent of systematic granuloma in spotted butterfish, Scatophagus argus, Linn  African Journal of Microbiology Research (submitted and revise)

Hsing-Yen Huang; Yan-Chun Chen; Pei-Chi Wang; Shih-Chun Yeh; Ming-An Tsai; Hong-Jen Liang; Shih-Chu Chen  (2014) Efficacies of formalin-inactivated vaccines against Streptococcus iniae infection in farmed grouper Epinephelus coioides by intraperitoneal immunization. Vaccine (submitted and revised)

Yi-Ting Wang, Hsing-Yen Huang, Ming-AnTsai, Pei-Chi Wang, Bo-Huang Jiang, and Shih-Chu Chen (2014) Phosphoglycerate kinase as a subunit vaccine enhances the whole cell immunity in tilapia. Fish and Shellfish Immunology  (submitted and revised)